Fig 1: Expression levels of Cdk5, Cdk5-pTyr15 and p25 over time following SAH. (A) Representative autoradiograms of the expression levels of Cdk5, Cdk5-pTyr15 and p25 in the temporal cortex following SAH. Quantitative analysis of the western blotting results; (B) Cdk5 protein levels significantly increased at 12 h and on day 1 after SAH; (C) Cdk5-pTyr15 protein levels increased at 6 and 12 h and on day 1 after SAH; and (D) p25 protein levels increased on days 1 and 3 after SAH. (E) Quantified ratio of Cdk5-pTyr15/Cdk5 expression. *P<0.05, **P<0.01 compared with the sham group. Cdk5, cyclin-dependent kinase 5; Cdk5-pTyr15, Cdk5 phosphorylated at Tyr15; SAH, subarachnoid hemorrhage.
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